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Can I get my infusions every month instead of every week?

Many individuals and their physicians have used alternative dosing regimens outside those recommended by the FDA. These include biweekly dosing at 120 mg/kg, dosing every third week at 180 mg/kg, and monthly dosing at 250 mg/kg. While these regimens have been used for years, some evidence suggests that weekly dosing at 60 mg/kg is the most effective. Most Alpha-1 aware physicians limit the use of more extended dosing intervals to individuals with significant logistical problems that make weekly dosing a hardship.

Even in these individuals, if lung function decline seems to remain accelerated or if side effects become a problem, it is wise to consider switching to the weekly dosing regimen to determine if this helps to alleviate the individual’s problems.

Augmentation TherapyAlphaNet